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Human CD112/Nectin-2/PVRL2 Antibody (NTX-1107C) - Bioactivity-binding
Key Features

Human CD112/Nectin-2/PVRL2 Antibody (NTX-1107C) (GXBS02628)

Datasheet MSDS
SKU GXBS02628
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Mouse
Reactivity Human
Applications ELISA, FCM, Functional assay, Research in vivo
Clone ID NTX-1107C
Isotype IgG2a, kappa
$677 - $2,208

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Description

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Human CD112/Nectin-2/PVRL2 Antibody (NTX-1107C)

Human CD112/Nectin-2/PVRL2 Antibody (NTX-1107C) is a research-grade biosimilar monoclonal antibody targeting Nectin-2. It is a mouse IgG2a, kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.

Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

Product Name:Human CD112/Nectin-2/PVRL2 Antibody (NTX-1107C)
SKU:GXBS02628
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Clone:NTX-1107C
Target:Nectin-2
Isotype:IgG2a, kappa
Host Species:Mouse
Reactivity:Human
Applications:ELISA, FCM, Functional assay, Research in vivo
Synonyms:Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2, Poliovirus receptor-related protein 2, CD112, NECTIN2, HVEB, PRR2, PVRL2
Purity:>95% as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4.
State of Matter:Liquid
Regulatory Status:For research use only.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:Q92692
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