Description
Human CD112/Nectin-2/PVRL2 Recombinant Protein (C-His)
Human CD112/Nectin-2/PVRL2 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Leu360, with a C-terminal His tag. Predicted molecular weight: 39.79 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. For research use only.
Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.
| Product Name: | Human CD112/Nectin-2/PVRL2 Recombinant Protein (C-His) |
| SKU: | GXRP03878 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Herpesvirus entry mediator B, Herpes virus entry mediator B, Nectin cell adhesion molecule 2, HVEB, PVRL2, Poliovirus receptor-related protein 2, CD112, PRR2, Nectin-2, HveB, NECTIN2 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Leu360 |
| Calculated MW: | 39.79 kDa |
| UniProt: | Q92692 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
