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Human CD140a/PDGFRA Recombinant Protein (C-His)
Key Features

Human CD140a/PDGFRA Recombinant Protein (C-His) (GXRP03393)

SKU GXRP03393
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Human CD140a/PDGFRA Recombinant Protein (C-His)

Human CD140a/PDGFRA Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Glu524, with a C-terminal His tag. Predicted molecular weight: 59.46 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Platelet-derived growth factor receptor alpha (CD140a/PDGFRA) is a ~122 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. For research use only.

Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi.

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