Description
Human CD160 Recombinant Protein (C-His)
Human CD160 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Gln179, with a C-terminal His tag. Predicted molecular weight: 22.56 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CD160 antigen is a ~19 kDa protein. Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. For research use only.
Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. Receptor for both classical and non-classical MHC class I molecules. In the context of acute viral infection, recognizes HLA-C and triggers NK cell cytotoxic activity, likely playing a role in anti-viral innate immune response. On CD8+ T cells, binds HLA-A2-B2M in complex with a viral peptide and provides a costimulatory signal to activated/memory T cells.
| Product Name: | Human CD160 Recombinant Protein (C-His) |
| SKU: | GXRP06201 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CD160 antigen, Natural killer cell receptor BY55, CD160, CD160 antigen, soluble form, CD160, BY55 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Gln179 |
| Calculated MW: | 22.56 kDa |
| UniProt: | O95971 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
