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Human CD163 (OR2805) Antibody - SDS-PAGE
Key Features

Human CD163 (OR2805) Antibody (GXBS00992)

Datasheet MSDS
SKU GXBS00992
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications ELISA, FACS, Functional assay, Research in vivo
Clone ID OR2805
Isotype IgG
$677 - $2,208

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Description

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Human CD163 (OR2805) Antibody

Human CD163 (OR2805) Antibody is a research-grade biosimilar monoclonal antibody targeting CD163. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a ~125 kDa protein. Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

Product Name:Human CD163 (OR2805) Antibody
SKU:GXBS00992
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Clone:OR2805
Target:Scavenger receptor cysteine-rich type 1 protein M130
Isotype:IgG
Host Species:Human
Reactivity:Human
Applications:ELISA, FACS, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:OR2805
Purity:>95% purity as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:Q86VB7
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