Description
Human CD180 Recombinant Protein (N-His)
Human CD180 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr430-Gly626, with an N-terminal His tag. Predicted molecular weight: 24.02 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CD180 antigen is a ~74 kDa protein. Pattern recognition receptor predominantly expressed on B-cells, dendritic cells, and certain monocytes/macrophages, structurally resembling Toll-like receptors (TLRs) that plays a role in modulating immune responses. For research use only.
While ressembling a TLR, lacks the intracellular TIR (Toll/IL-1R) signaling domain and thus does not directly transduce signals. Instead, modulates immune responses, often in conjunction with other TLRs. For example, in cooperation with MD-1/LY86, interacts directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligand.
| Product Name: | Human CD180 Recombinant Protein (N-His) |
| SKU: | GXRP02749 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Radioprotective 105 kDa protein, Lymphocyte antigen 64, RP105, LY64, CD180 antigen, CD180 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr430-Gly626 |
| Calculated MW: | 24.02 kDa |
| UniProt: | Q99467 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
