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Human CD192/CCR2 Recombinant Protein (N-His)
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Human CD192/CCR2 Recombinant Protein (N-His) (GXRP12432)

Datasheet MSDS
SKU GXRP12432
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CD192/CCR2 Recombinant Protein (N-His)

Human CD192/CCR2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu44&Gly309-Ala374, with an N-terminal His tag. Predicted molecular weight: 14.20 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. C-C chemokine receptor type 2 is a ~41 kDa protein. Key functional receptor for CCL2 but can also bind CCL7, and CCL12. For research use only.

Also transduces signaling mediated by CCL13. Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion. Also acts as a receptor for the beta-defensin DEFB106A/DEFB106B. Regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiation of T-cells into T-helper 17 cells (Th17) during inflammation.

Product Name:Human CD192/CCR2 Recombinant Protein (N-His)
SKU:GXRP12432
Size:50 µg, 100 µg, 1 mg
Species:Human
Synonyms:C-C CKR-2, C-C chemokine receptor type 2, CC-CKR-2, CCR-2, CCR2, CD192, CMKBR2, MCP-1-R, Monocyte chemoattractant protein 1 receptor
Tag:N-His
Expression Host:E. coli
Protein Length:Met1-Leu44&Gly309-Ala374
Calculated MW:14.20 kDa
UniProt:P41597
Applications:ELISA, Immunogen, SDS-PAGE, WB
Purity:>90% as determined by SDS-PAGE.
Form:Lyophilized
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Shipping:In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Note:For research use only
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