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Human CD229/LY9 Recombinant Protein (C-His)
Key Features

Human CD229/LY9 Recombinant Protein (C-His) (GXRP12287)

SKU GXRP12287
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Human CD229/LY9 Recombinant Protein (C-His)

Human CD229/LY9 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Lys48-Lys454, with a C-terminal His tag. Predicted molecular weight: 48.00 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. T-lymphocyte surface antigen Ly-9 is a ~72 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. For research use only.

SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion; the costimulatory activity requires SH2D1A.

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