Description
Human CD271/NGFR Recombinant Protein (N-His)
Human CD271/NGFR Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys29-Asn250, with an N-terminal His tag. Predicted molecular weight: 25.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tumor necrosis factor receptor superfamily member 16 (CD271/NGFR) is a ~45 kDa protein. Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. For research use only.
Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA.
| Product Name: | Human CD271/NGFR Recombinant Protein (N-His) |
| SKU: | GXRP00699 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Low affinity neurotrophin receptor p75NTR, TNFRSF16, CD271, Gp80-LNGFR, p75 ICD, Low-affinity nerve growth factor receptor, NGFR, NGF receptor, Tumor necrosis factor receptor superfamily member 16 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys29-Asn250 |
| Calculated MW: | 25.85 kDa |
| UniProt: | P08138 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
