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PE Anti-Human CD326 Antibody [9C4] (AGEL1820)

Datasheet MSDS
SKU AGEL1820
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Applications FC
€94 - €425

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Human CD326 Antibody [9C4]

The Human CD326 Monoclonal Antibody (PE Conjugated, 9C4, AGEL1820) offered by AssayGenie is a powerful tool for researchers studying CD326, a cell surface marker associated with stemness and epithelial cell adhesion. This antibody, derived from a monoclonal source, is optimized for use with human samples and is conjugated with the fluorophore phycoerythrin (PE), allowing for easy visualization and analysis in flow cytometry and fluorescence microscopy applications.CD326, also known as EpCAM (Epithelial Cell Adhesion Molecule), is a key protein involved in cell-cell adhesion and signaling pathways associated with cell differentiation and proliferation. Its expression is often dysregulated in various cancer types, making it a promising target for diagnostic and therapeutic approaches.

By utilizing the CD326 Monoclonal Antibody, researchers can accurately detect and quantify CD326 levels in different cell populations, providing valuable insights into cancer biology, stem cell research, and epithelial cell biology.The high specificity and sensitivity of the 9C4 clone and the PE conjugation of this antibody make it an ideal choice for experiments requiring precise and reliable detection of CD326. With its potential applications in cancer research, stem cell identification, and cell adhesion studies, the Human CD326 Monoclonal Antibody (PE Conjugated, 9C4, AGEL1820) from AssayGenie is a valuable asset for scientists exploring the intricacies of CD326-related processes in human cells.

Product Title:PE Anti-Human CD326 Antibody [9C4]
SKU:AGEL1820
Size:20 Tests, 100 Tests, 200 Tests
Clone No:9C4
Synonyms:EpCAM;Ep-CAM;GA733-2;M1S2;M4S1;MIC18;TACSTD1; TROP1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16422
Gene ID:4072
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
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