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Human CD328/SIGLEC7 Recombinant Protein (C-His)
Key Features

Human CD328/SIGLEC7 Recombinant Protein (C-His) (GXRP12335)

SKU GXRP12335
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Human CD328/SIGLEC7 Recombinant Protein (C-His)

Human CD328/SIGLEC7 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Leu353, with a C-terminal His tag. Predicted molecular weight: 40.02 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sialic acid-binding Ig-like lectin 7 is a ~51 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. For research use only.

Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

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