Description

Biotin Anti-Human CD35 Antibody [E11]

The Human CD35 Monoclonal Antibody (Biotin Conjugated) E11-AG0258 is a cutting-edge tool designed for precise detection and analysis of CD35, a crucial cell surface receptor with diverse functions in the immune system. This monoclonal antibody, meticulously crafted for high specificity and sensitivity, is engineered for use in a variety of applications, including immunohistochemistry, flow cytometry, and immunofluorescence.CD35, also known as complement receptor type 1 (CR1), plays a pivotal role in the regulation of the complement system, a key component of innate immunity. By binding to CD35, this antibody facilitates the identification and characterization of CD35 expression and localization in different cell types and tissues.

This makes it an invaluable asset for researchers exploring the mechanisms of immune response, inflammation, and autoimmune disorders.With its biotin conjugation, this antibody offers enhanced versatility and compatibility with various experimental techniques, allowing for robust and reliable results in diverse research settings. By providing insights into the intricate functions of CD35, this antibody helps advance our understanding of immune processes and opens doors to potential therapeutic interventions in conditions ranging from infectious diseases to autoimmune disorders.

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Product Title:	Biotin Anti-Human CD35 Antibody [E11]
SKU:	AGEL0258
Size:	25µg, 100µg
Clone No:	E11
Synonyms:	Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	Biotin
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Swissprot:	P17927
Gene ID:	1378
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Biotin Anti-Human CD35 Antibody [E11] (AGEL0258)

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Description