Description
Human CD358/TNFRSF21 Recombinant Protein (C-His)
Human CD358/TNFRSF21 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Gln42-His349, with a C-terminal His tag. Predicted molecular weight: 36.66 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tumor necrosis factor receptor superfamily member 21 (CD358/TNFRSF21) is a ~71 kDa protein. Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. For research use only.
Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation.
| Product Name: | Human CD358/TNFRSF21 Recombinant Protein (C-His) |
| SKU: | GXRP03758 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DR6, Death receptor 6, Tumor necrosis factor receptor superfamily member 21, TNFRSF21, CD358 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Gln42-His349 |
| Calculated MW: | 36.66 kDa |
| UniProt: | O75509 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >95% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
