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Human CD44 (VB6-008) Antibody - SDS-PAGE
Key Features

Human CD44 (VB6-008) Antibody (GXBS01099)

Datasheet MSDS
SKU GXBS01099
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications ELISA, FACS, Functional assay, Research in vivo
Clone ID VB6-008
Isotype IgG
$677 - $2,208

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Description

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Human CD44 (VB6-008) Antibody

Human CD44 (VB6-008) Antibody is a research-grade biosimilar monoclonal antibody. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

CD44 antigen is a ~81 kDa protein. Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases. Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion. Upon interaction with LGALS9 ligand, activates downstream signaling components including LCK, ERK and MAPK to promotes NK cell activation.

Product Name:Human CD44 (VB6-008) Antibody
SKU:GXBS01099
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Clone:VB6-008
Target:Hyaluronate receptor
Isotype:IgG
Host Species:Human
Reactivity:Human
Applications:ELISA, FACS, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:VB6-008, VB6008, VB6008
Purity:>95% purity as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:P16070
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