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Human CD49d/ITGA4 Recombinant Protein (N-His)
Key Features

Human CD49d/ITGA4 Recombinant Protein (N-His) (GXRP00943)

SKU GXRP00943
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human CD49d/ITGA4 Recombinant Protein (N-His)

Human CD49d/ITGA4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn35-Leu315, with an N-terminal His tag. Predicted molecular weight: 33.18 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Integrin alpha-4 (CD49d/ITGA4) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. For research use only.

They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1.

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