Description

PE Anti-Human CD49d Antibody [9F10]

The Human CD49d Monoclonal Antibody (PE Conjugated, clone 9F10) from AssayGenie is a crucial tool for researchers studying CD49d expression and function. CD49d, also known as integrin alpha-4, is a cell surface protein involved in cell adhesion and migration, particularly in the immune system.This monoclonal antibody, conjugated with phycoerythrin (PE), allows for sensitive detection of CD49d in human samples using flow cytometry or immunofluorescence techniques. Its specificity and high affinity make it an excellent choice for identifying and quantifying CD49d-expressing cells in various tissues and cell populations.

With its proven performance in research applications, the Human CD49d Monoclonal Antibody (PE Conjugated, clone 9F10) offered by AssayGenie is a valuable resource for studying the role of CD49d in immune responses, inflammation, and cell migration. Researchers in immunology, oncology, and cell biology will benefit from its reliability and accuracy in experimental analysis.

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Product Title:	PE Anti-Human CD49d Antibody [9F10]
SKU:	AGEL1737
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	9F10
Synonyms:	Integrin alpha-4;CD49 antigen-like family member D;Integrin alpha-IV;VLA-4 subunit alpha;CD49d;ITGA4;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	PE
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P13612
Gene ID:	3676
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

PE Anti-Human CD49d Antibody [9F10] (AGEL1737)

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