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Human CD50/ICAM3 (ICM3) Antibody - flow
Key Features

Human CD50/ICAM3 (ICM3) Antibody (GXBS02727)

Datasheet MSDS
SKU GXBS02727
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications ELISA, FCM, Functional assay, Research in vivo
Clone ID ICM3
Isotype IgG1
€310 - €862

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Description

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Human CD50/ICAM3 (ICM3) Antibody

Human CD50/ICAM3 (ICM3) Antibody is a research-grade biosimilar monoclonal antibody targeting CD50. It is a humanized IgG1 antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Intercellular adhesion molecule 3 (CD50/ICAM3) is a ~59 kDa protein. Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring apoptotic neutrophil phagocytosis by macrophages. Is also a ligand for integrin ITGAD/ITGB2. Ligand of CD209 on dendritic cells (DC) through an integrin-independent mechanism that requires Ca(2+) and that forms a first contact between DC and resting T cell, facilitating the downstream DC-T cell clustering process and DC-induced proliferation of resting T Cells.

Product Name:Human CD50/ICAM3 (ICM3) Antibody
SKU:GXBS02727
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Clone:ICM3
Target:CD50
Isotype:IgG1
Host Species:Human
Reactivity:Human
Applications:ELISA, FCM, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:CD50, CDw50, Intercellular adhesion molecule 3, ICAM-R, ICAM3, ICAM-3
Recommended Dilutions:ELISA: 1:2000-1:20000
Purity:>95% as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4.
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:P32942
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