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GenieFluor 647 Anti-Human CD86 Antibody [BU63] (AGEL0651)

Datasheet MSDS
SKU AGEL0651
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone BU63
Conjugation AF 647
€100 - €428

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Description

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GenieFluor 647 Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody (AF647 Conjugated) from Assay Genie (Catalog Number: BU63-AGEL0651) is a cutting-edge tool designed for researchers studying immune responses and immune cell activation. This antibody, conjugated with AF647 for fluorescent detection, specifically targets the CD86 protein, a crucial co-stimulatory molecule expressed on antigen-presenting cells.CD86 plays a pivotal role in the activation of T cells and the regulation of immune responses, making it a key target for investigation in immunology and related fields. The Human CD86 Monoclonal Antibody (AF647 Conjugated) is rigorously validated for use in flow cytometry and immunofluorescence applications, providing researchers with a reliable tool for visualizing and analyzing CD86 expression in various cell populations.

By utilizing this high-quality antibody, researchers can delve deeper into the mechanisms of immune regulation, T cell activation, and antigen presentation. The Human CD86 Monoclonal Antibody (AF647 Conjugated) is instrumental in advancing our understanding of immune system function and holds immense potential for applications in vaccine development, immunotherapy, and autoimmune disease research.

Product Title:GenieFluor 647 Anti-Human CD86 Antibody [BU63]
SKU:AGEL0651
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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