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Key Features

APC Anti-Human CD95 Antibody [DX2] (AGEL1839)

Datasheet MSDS
SKU AGEL1839
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone DX2
Conjugation APC
€132 - €585

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Description

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APC Anti-Human CD95 Antibody [DX2]

The Human CD95 Monoclonal Antibody (APC-conjugated) DX2 (AG-EL1839) is a powerful tool for researchers studying CD95, a cell surface receptor crucial for apoptosis signaling in immune cells. This monoclonal antibody, derived from mouse hybridoma cells, exhibits high specificity and affinity for human CD95, making it ideal for flow cytometry studies. By binding to the CD95 antigen, this antibody allows for precise detection and quantification of CD95-expressing cells in diverse biological samples.CD95, also known as Fas receptor, is a key player in programmed cell death pathways and immune system regulation. Its dysregulation has been implicated in various diseases, including cancer and autoimmune disorders.

By targeting CD95 with this monoclonal antibody, researchers can gain insights into the role of CD95 in disease development and progression. Moreover, understanding the mechanisms by which CD95 impacts cell survival and death processes can provide valuable information for developing targeted therapies in oncology and immunology research.Overall, the Human CD95 Monoclonal Antibody (APC-conjugated) DX2 (AG-EL1839) offers a reliable tool for investigating the functions and implications of CD95 in health and disease, ultimately contributing to advancements in therapeutic approaches and disease management strategies.

Product Title:APC Anti-Human CD95 Antibody [DX2]
SKU:AGEL1839
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DX2
Synonyms:APT1;FAS1;TNFRSF6;Apo-1 antigen;FASLG receptor;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25445
Gene ID:355
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
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