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Human CDC25B Recombinant Protein (N-His)
Key Features

Human CDC25B Recombinant Protein (N-His) (GXRP01398)

SKU GXRP01398
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human CDC25B Recombinant Protein (N-His)

Human CDC25B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys377-Gly566, with an N-terminal His tag. Predicted molecular weight: 24.62 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. M-phase inducer phosphatase 2 (CDC25B) is a ~64 kDa protein. Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. For research use only.

Directly dephosphorylates CDK1 and stimulates its kinase activity. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. The three isoforms seem to have a different level of activity.

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