Description
Human CDK13 Recombinant Protein (N-His)
Human CDK13 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val702-Asp1000, with an N-terminal His tag. Predicted molecular weight: 37.00 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cyclin-dependent kinase 13 is a ~164 kDa protein. Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. For research use only.
Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
| Product Name: | Human CDK13 Recombinant Protein (N-His) |
| SKU: | GXRP11209 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CDC2-related protein kinase 5, CDC2L, CDC2L5, CDK13, CHED, Cell division cycle 2-like protein kinase 5, Cell division protein kinase 13, Cholinesterase-related cell division controller, Cyclin-dependent kinase 13, EC:2.7.11.22, EC:2.7.11.23, KIAA1791, hCDK13 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val702-Asp1000 |
| Calculated MW: | 37.00 kDa |
| UniProt: | Q14004 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
