Description
Human CDKN1B Recombinant Protein (N-His)
Human CDKN1B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Thr198, with an N-terminal His tag. Predicted molecular weight: 24.19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a ~22 kDa protein. Important regulator of cell cycle progression. For research use only.
Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation.
| Product Name: | Human CDKN1B Recombinant Protein (N-His) |
| SKU: | GXRP01638 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Cyclin-dependent kinase inhibitor 1B, KIP1, CDKN1B, p27Kip1, Cyclin-dependent kinase inhibitor p27 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Thr198 |
| Calculated MW: | 24.19 kDa |
| UniProt: | P46527 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
