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Human CECR2 Recombinant Protein (N-His)
Key Features

Human CECR2 Recombinant Protein (N-His) (GXRP11934)

SKU GXRP11934
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CECR2 Recombinant Protein (N-His)

Human CECR2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met424-His538, with an N-terminal His tag. Predicted molecular weight: 16.19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Chromatin remodeling regulator CECR2 is a ~164 kDa protein. Regulatory subunit of the ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. For research use only.

The complexes do not have the ability to slide mononucleosomes to the center of a DNA template. The CERF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the CERF-5 ISWI chromatin remodeling complex. Plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development. In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes.

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