Description
Human CELF1 Recombinant Protein (N-His)
Human CELF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys17-Asp187, with an N-terminal His tag. Predicted molecular weight: 21.64 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CUGBP Elav-like family member 1 (CELF1) is a ~52 kDa protein. RNA-binding protein implicated in the regulation of several post-transcriptional events. For research use only.
Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts both as an activator and as a repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs.
| Product Name: | Human CELF1 Recombinant Protein (N-His) |
| SKU: | GXRP06373 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CELF-1, CUGBP1, CUGBP Elav-like family member 1, Deadenylation factor CUG-BP, Embryo deadenylation element-binding protein homolog, EDEN-BP homolog, CELF1, RNA-binding protein BRUNOL-2, 50 kDa nuclear polyadenylated RNA-binding protein, CUG triplet repeat RNA-binding protein 1, BRUNOL2, CUGBP, NAB50, CUG-BP- and ETR-3-like factor 1, Bruno-like protein 2, CUG-BP1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys17-Asp187 |
| Calculated MW: | 21.64 kDa |
| UniProt: | Q92879 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
