Description
Human CENPF Recombinant Protein (N-His)
Human CENPF Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln436-Lys637, with an N-terminal His tag. Predicted molecular weight: 26.18 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Centromere protein F (CENPF) is a ~357 kDa protein. Required for kinetochore function and chromosome segregation in mitosis. For research use only.
Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes.
| Product Name: | Human CENPF Recombinant Protein (N-His) |
| SKU: | GXRP01688 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CENPF, Mitosin, CENP-F, Centromere protein F, Kinetochore protein CENPF, AH antigen |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln436-Lys637 |
| Calculated MW: | 26.18 kDa |
| UniProt: | P49454 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
