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Human CENPI Recombinant Protein (N-His)
Key Features

Human CENPI Recombinant Protein (N-His) (GXRP02650)

SKU GXRP02650
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CENPI Recombinant Protein (N-His)

Human CENPI Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu292-Gly528, with an N-terminal His tag. Predicted molecular weight: 29.83 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Centromere protein I (CENPI) is a ~86 kDa protein. Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. For research use only.

May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone.

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