Description
Human CEP290 Recombinant Protein (N-His)
Human CEP290 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr1289-Arg1416, with an N-terminal His tag. Predicted molecular weight: 17.89 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Centrosomal protein of 290 kDa (CEP290) is a ~290 kDa protein. Involved in early and late steps in cilia formation. For research use only.
Its association with CCP110 is required for inhibition of primary cilia formation by CCP110. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes.
| Product Name: | Human CEP290 Recombinant Protein (N-His) |
| SKU: | GXRP05103 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Nephrocystin-6, KIAA0373, CEP290, Bardet-Biedl syndrome 14 protein, Tumor antigen se2-2, BBS14, NPHP6, Centrosomal protein of 290 kDa, Cancer/testis antigen 87, Cep290, CT87 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr1289-Arg1416 |
| Calculated MW: | 17.89 kDa |
| UniProt: | O15078 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
