Description
Human CERS2 Recombinant Protein (N-His-SUMO)
Human CERS2 Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Asn81-Ser128, with an N-terminal His-SUMO tag. Predicted molecular weight: 18.08 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ceramide synthase 2 (CERS2) is a ~44 kDa protein. Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very-long-chain fatty acyl-CoA (chain length C22-C27). For research use only.
N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a non-redundant role in the synthesis of ceramides with very-long-chain fatty acids in kidney, liver and brain. Regulates the abundance of myelin-specific sphingolipids galactosylceramide and sulfatide that affects myelin sheath architecture and motor neuron functions.
| Product Name: | Human CERS2 Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP05692 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | SP260, CERS2, LASS2, CerS2, TMSG1, Ceramide synthase 2, LAG1 longevity assurance homolog 2, Tumor metastasis-suppressor gene 1 protein, Sphingosine N-acyltransferase CERS2 |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Asn81-Ser128 |
| Calculated MW: | 18.08 kDa |
| UniProt: | Q96G23 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
