Description
Human CHD1L Recombinant Protein (N-His)
Human CHD1L Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser716-Pro897, with an N-terminal His tag. Predicted molecular weight: 22.48 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATP-dependent chromatin remodeler CHD1L is a ~101 kDa protein. ATP-dependent chromatin remodeler that mediates chromatin-remodeling following DNA damage. For research use only.
Recruited to DNA damage sites through interaction with poly-ADP-ribose: specifically recognizes and binds histones that are poly-ADP-ribosylated on serine residues in response to DNA damage. Poly-ADP-ribose-binding activates the ATP-dependent chromatin remodeler activity, thereby regulating chromatin during DNA repair. Catalyzes nucleosome sliding away from DNA breaks in an ATP-dependent manner. Chromatin remodeling activity promotes PARP2 removal from chromatin.
| Product Name: | Human CHD1L Recombinant Protein (N-His) |
| SKU: | GXRP11046 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ALC1, Amplified in liver cancer protein 1, CHD1L, Chromodomain-helicase-DNA-binding protein 1-like, EC:3.6.4.- |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser716-Pro897 |
| Calculated MW: | 22.48 kDa |
| UniProt: | Q86WJ1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
