Description
Human CHRM2 Recombinant Protein (N-His-KSI)
Human CHRM2 Recombinant Protein (N-His-KSI) is a recombinant protein expressed in E. coli, spanning Ser210-Arg387, with an N-terminal His-KSI tag. Predicted molecular weight: 35.11 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Muscarinic acetylcholine receptor M2 is a ~51 kDa protein. Muscarinic receptor for acetylcholine, a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia. For research use only.
Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. CHRM2 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G proteins and mediates signaling by inhibiting adenylate cyclase activity.
| Product Name: | Human CHRM2 Recombinant Protein (N-His-KSI) |
| SKU: | GXRP10034 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Muscarinic acetylcholine receptor M2, CHRM2 |
| Tag: | N-His-KSI |
| Expression Host: | E. coli |
| Protein Length: | Ser210-Arg387 |
| Calculated MW: | 35.11 kDa |
| UniProt: | P08172 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
