Description
Human CITED1 Recombinant Protein (N-His)
Human CITED1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Cys193, with an N-terminal His tag. Predicted molecular weight: 22.06 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cbp/p300-interacting transactivator 1 (CITED1) is a ~19 kDa protein. Transcriptional coactivator of the p300/CBP-mediated transcription complex. For research use only.
Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death.
| Product Name: | Human CITED1 Recombinant Protein (N-His) |
| SKU: | GXRP02790 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Cbp/p300-interacting transactivator 1, CITED1, MSG1, Melanocyte-specific protein 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Cys193 |
| Calculated MW: | 22.06 kDa |
| UniProt: | Q99966 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
