Description
Human CLIC3 Recombinant Protein (N-His)
Human CLIC3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp45-Arg236, with an N-terminal His tag. Predicted molecular weight: 24.13 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Chloride intracellular channel protein 3 is a ~26 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. For research use only.
Reduced in a glutathione-dependent way and secreted into the extracellular matrix where it activates TGM2 and promotes blood vessel growth during tissue remodeling as occurs in tumorigenesis. Can reduce specific cysteines in TGM2 and regulate cofactor binding. Can insert into membranes and form outwardly rectifying chloride ion channels. May participate in cellular growth control.
| Product Name: | Human CLIC3 Recombinant Protein (N-His) |
| SKU: | GXRP09774 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Chloride intracellular channel protein 3; CLIC3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp45-Arg236 |
| Calculated MW: | 24.13 kDa |
| UniProt: | O95833 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
