Description
Human CLPX Recombinant Protein (N-His)
Human CLPX Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser287-Ala605, with an N-terminal His tag. Predicted molecular weight: 37.19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATP-dependent clpX-like chaperone, mitochondrial is a ~69 kDa protein. ATP-dependent chaperone that functions as an unfoldase. For research use only.
As part of the ClpXP protease complex, it recognizes specific protein substrates, unfolds them using energy derived from ATP hydrolysis, and then translocates them to the proteolytic subunit (CLPP) of the ClpXP complex for degradation. Thanks to its chaperone activity, it also functions in the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. This chaperone is also involved in the control of mtDNA nucleoid distribution, by regulating mitochondrial transcription factor A (TFAM) activity.
| Product Name: | Human CLPX Recombinant Protein (N-His) |
| SKU: | GXRP11241 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, ATP-dependent clpX-like chaperone, mitochondrial, CLPX, Caseinolytic mitochondrial matrix peptidase chaperone subunit X, EC:3.6.4.10 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser287-Ala605 |
| Calculated MW: | 37.19 kDa |
| UniProt: | O76031 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
