Description
Human CMPK2 Recombinant Protein (N-His)
Human CMPK2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu99-Pro449, with an N-terminal His tag. Predicted molecular weight: 41.48 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. UMP-CMP kinase 2, mitochondrial is a ~49 kDa protein. Mitochondrial nucleotide monophosphate kinase needed for salvage dNTP synthesis that mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways. For research use only.
Restricts the replication of multiple viruses including flaviviruses or coronaviruses. Together with viperin/RSAD2 and ddhCTP, suppresses the replication of several coronaviruses through inhibition of the viral RNA-dependent RNA polymerase activities. Concerning flaviviruses, restricts RNA translation when localized to the mitochondria independently of its kinase activity. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor.
| Product Name: | Human CMPK2 Recombinant Protein (N-His) |
| SKU: | GXRP09372 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | UMP-CMP kinase 2, mitochondrial; 2.7.4.14; Nucleoside-diphosphate kinase; 2.7.4.6; CMPK2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu99-Pro449 |
| Calculated MW: | 41.48 kDa |
| UniProt: | Q5EBM0 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
