Description
Human CNGA2 Recombinant Protein (N-His)
Human CNGA2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe475-Pro664, with an N-terminal His tag. Predicted molecular weight: 23.49 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cyclic nucleotide-gated channel alpha-2 is a ~76 kDa protein. Pore-forming subunit of the olfactory cyclic nucleotide-gated channel. For research use only.
Operates in the cilia of olfactory sensory neurons where chemical stimulation of the odorant is converted to an electrical signal. Mediates odorant-induced cAMP-dependent Ca(2+) influx triggering neuron depolarization. The rise of intracellular Ca(2+) levels potentiates the olfactory response by activating Ca(2+)-dependent Cl(-) channels, but it also serves as a negative feedback signal to desensitize the channel for rapid adaptation to odorants. Conducts cAMP- and cGMP-gated ion currents, with permeability for monovalent and divalent cations.
| Product Name: | Human CNGA2 Recombinant Protein (N-His) |
| SKU: | GXRP11532 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CNCA, CNCA1, CNCG2, CNG channel alpha-2, CNG-2, CNG2, CNGA2, Cyclic nucleotide-gated channel alpha-2, OCNC1, Olfactory cyclic nucleotide-gated channel subunit 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe475-Pro664 |
| Calculated MW: | 23.49 kDa |
| UniProt: | Q16280 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
