Description
Human COQ6 Recombinant Protein (N-His)
Human COQ6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys468, with an N-terminal His tag. Predicted molecular weight: 53.03 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial is a ~50 kDa protein. FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. For research use only.
Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-decaprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid. Also acts downstream of COQ4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-decaprenyl)phenol to 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to COQ6 from NADPH via a ferredoxin/ferredoxin reductase system composed of FDX2 and FDXR.
| Product Name: | Human COQ6 Recombinant Protein (N-His) |
| SKU: | GXRP03120 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial, COQ6, Coenzyme Q10 monooxygenase 6 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys468 |
| Calculated MW: | 53.03 kDa |
| UniProt: | Q9Y2Z9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
