Description
Human CORO1C Recombinant Protein (N-His)
Human CORO1C Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg352, with an N-terminal His tag. Predicted molecular weight: 41.80 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Coronin-1C is a ~53 kDa protein. Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1. For research use only.
Increases the presence of activated RAC1 at the leading edge of migrating cells. Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments. Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission. Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.
| Product Name: | Human CORO1C Recombinant Protein (N-His) |
| SKU: | GXRP09778 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Coronin-1C; Coronin-3; hCRNN4; CORO1C; CRN2; CRNN4 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Arg352 |
| Calculated MW: | 41.80 kDa |
| UniProt: | Q9ULV4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
