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Human CREB3 Recombinant Protein (N-His)
Key Features

Human CREB3 Recombinant Protein (N-His) (GXRP13868)

SKU GXRP13868
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CREB3 Recombinant Protein (N-His)

Human CREB3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys145-Thr251, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cyclic AMP-responsive element-binding protein 3 is a ~41 kDa protein. Endoplasmic reticulum (ER)-bound sequence-specific transcription factor that directly binds DNA and activates transcription. For research use only.

Plays a role in the unfolded protein response (UPR), promoting cell survival versus ER stress-induced apoptotic cell death. Also involved in cell proliferation, migration and differentiation, tumor suppression and inflammatory gene expression. Acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Associates with chromatin to the HERPUD1 promoter.

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