Description
Human CTTN Recombinant Protein (N-His)
Human CTTN Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asn491, with an N-terminal His tag. Predicted molecular weight: 57.08 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Src substrate cortactin (CTTN) is a ~61 kDa protein. Contributes to the organization of the actin cytoskeleton and cell shape. For research use only.
Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in focal adhesion assembly and turnover. 1. von Holleben, M. et al. (2011) The Journal of biological chemistry 286, 13489-501. PMID: 21296879 2. Dudek, SM. et al. (2010) Molecular biology of the cell 21, 4042-56. PMID: 20861316 3. Williams, MR. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 17412-7. PMID: 17959782 4. Herrmann, S. et al. (2012) The Journal of biological chemistry 287, 44151-63. PMID: 23144454 5. Hashimoto, S. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 7036-41. PMID: 16636290
| Product Name: | Human CTTN Recombinant Protein (N-His) |
| SKU: | GXRP06724 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Src substrate cortactin, Oncogene EMS1, CTTN, Amplaxin, EMS1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asn491 |
| Calculated MW: | 57.08 kDa |
| UniProt: | Q14247 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
