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Human DAG1/Dystroglycan (DAG-6F4) Antibody - SDS-PAGE
Key Features

Human DAG1/Dystroglycan (DAG-6F4) Antibody (GXBS00916)

SKU GXBS00916
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications ELISA, FACS, Functional assay, Research in vivo
Clone ID DAG-6F4
Isotype IgG
€513 - €1,673

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Description

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Human DAG1/Dystroglycan (DAG-6F4) Antibody

Human DAG1/Dystroglycan (DAG-6F4) Antibody is a research-grade biosimilar monoclonal antibody targeting Dystrophin-associated glycoprotein 1. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Dystroglycan 1 (DAG1) is a ~97 kDa protein. The dystroglycan complex is involved in a number of signaling events and processes including laminin deposition and extracellular matrix assembly, acetylcholine receptor clustering, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, epithelial polarization, and epithelium branching morphogenesis. Required for the formation of photoreceptor ribbon synapses, and long-term maintenance of inhibitory synapses in cerebellar Purkinje cells. Also involved in the positive regulation of cartilage formation through agrin (AGRN) binding and up-regulation of SOX9, a transcription factor that plays a key role in chondrocytes differentiation.

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