Description
Human DCAF15 Recombinant Protein (N-His)
Human DCAF15 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Tyr386-Val564, with an N-terminal His tag. Predicted molecular weight: 22.79 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DDB1- and CUL4-associated factor 15 is a ~66 kDa protein. Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins. For research use only.
The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3. May play a role in the activation of antigen-presenting cells (APC) and their interaction with NK cells.
| Product Name: | Human DCAF15 Recombinant Protein (N-His) |
| SKU: | GXRP09690 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DDB1- and CUL4-associated factor 15; DCAF15; C19orf72 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Tyr386-Val564 |
| Calculated MW: | 22.79 kDa |
| UniProt: | Q66K64 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
