Description
Human DCTN1 Recombinant Protein (N-His)
Human DCTN1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Pro599-Glu911, with an N-terminal His tag. Predicted molecular weight: 36.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Dynactin subunit 1 (DCTN1) is a ~141 kDa protein. Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. For research use only.
Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule.
| Product Name: | Human DCTN1 Recombinant Protein (N-His) |
| SKU: | GXRP05253 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | p150-glued, p135, DAP-150, 150 kDa dynein-associated polypeptide, Dynactin subunit 1, DCTN1, DP-150 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Pro599-Glu911 |
| Calculated MW: | 36.85 kDa |
| UniProt: | Q14203 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
