Description
Human DDX39B/BAT1/UAP56 Recombinant Protein (N-His)
Human DDX39B/BAT1/UAP56 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu259-Arg428, with an N-terminal His tag. Predicted molecular weight: 22.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Spliceosome RNA helicase DDX39B (BAT1/UAP56) is a ~48 kDa protein. Involved in nuclear export of spliced and unspliced mRNA. For research use only.
Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. The TREX complex is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway. The THOC1-THOC2-THOC3 core complex alone is sufficient to promote ATPase activity of DDX39B; in the complex THOC2 is the only component that directly interacts with DDX39B. Associates with SARNP/CIP29, which facilitates RNA binding of DDX39B and likely plays a role in mRNA export.
| Product Name: | Human DDX39B/BAT1/UAP56 Recombinant Protein (N-His) |
| SKU: | GXRP04049 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BAT1, Spliceosome RNA helicase DDX39B, ATP-dependent RNA helicase p47, DEAD box protein UAP56, DDX39B, UAP56, HLA-B-associated transcript 1 protein, 56 kDa U2AF65-associated protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu259-Arg428 |
| Calculated MW: | 22.17 kDa |
| UniProt: | Q13838 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
