Description
Human DDX5 Recombinant Protein (N-His)
Human DDX5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg68-Ser483, with an N-terminal His tag. Predicted molecular weight: 49.51 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Probable ATP-dependent RNA helicase DDX5 is a ~69 kDa protein. Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. For research use only.
Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1.
| Product Name: | Human DDX5 Recombinant Protein (N-His) |
| SKU: | GXRP10502 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DDX5, DEAD box protein 5, EC:3.6.4.13, G17P1, HELR, HLR1, Probable ATP-dependent RNA helicase DDX5, RNA helicase p68 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg68-Ser483 |
| Calculated MW: | 49.51 kDa |
| UniProt: | P17844 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
