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Human DEUP1 Recombinant Protein (N-His-SUMO)
Key Features

Human DEUP1 Recombinant Protein (N-His-SUMO) (GXRP10965)

SKU GXRP10965
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His-SUMO
€347 - €1,827

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Description

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Human DEUP1 Recombinant Protein (N-His-SUMO)

Human DEUP1 Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Lys420-Arg508, with an N-terminal His-SUMO tag. Predicted molecular weight: 22.90 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Deuterosome assembly protein 1 is a ~70 kDa protein. Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. For research use only.

Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.

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