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Human DHPS Recombinant Protein (N-His)
Key Features

Human DHPS Recombinant Protein (N-His) (GXRP01684)

SKU GXRP01684
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human DHPS Recombinant Protein (N-His)

Human DHPS Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asp369, with an N-terminal His tag. Predicted molecular weight: 43.13 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Deoxyhypusine synthase (DHPS) is a ~40 kDa protein. Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. For research use only.

This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.

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