Description
Human DMAP1 Recombinant Protein (N-His)
Human DMAP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys91-Ala207, with an N-terminal His tag. Predicted molecular weight: 16.69 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA methyltransferase 1-associated protein 1 (DMAP1) is a ~52 kDa protein. Involved in transcription repression and activation. For research use only.
Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.
| Product Name: | Human DMAP1 Recombinant Protein (N-His) |
| SKU: | GXRP05529 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KIAA1425, DMAP1, DNMAP1, DNA methyltransferase 1-associated protein 1, DNMT1-associated protein 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys91-Ala207 |
| Calculated MW: | 16.69 kDa |
| UniProt: | Q9NPF5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
