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Human DNAJB11 Recombinant Protein (N-His)
Key Features

Human DNAJB11 Recombinant Protein (N-His) (GXRP04282)

SKU GXRP04282
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human DNAJB11 Recombinant Protein (N-His)

Human DNAJB11 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly23-Glu333, with an N-terminal His tag. Predicted molecular weight: 37.67 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DnaJ homolog subfamily B member 11 (DNAJB11) is a ~40 kDa protein. As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. For research use only.

Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1.

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