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Human DOC2B Recombinant Protein (N-GST & C-His)
Key Features

Human DOC2B Recombinant Protein (N-GST & C-His) (GXRP10917)

SKU GXRP10917
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-GST & C-His
$458 - $2,412

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Description

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Human DOC2B Recombinant Protein (N-GST & C-His)

Human DOC2B Recombinant Protein (N-GST & C-His) is a recombinant protein expressed in E. coli, spanning Cys23-Leu127, with an N-terminal GST tag and a C-terminal His tag. Predicted molecular weight: 39.00 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Double C2-like domain-containing protein beta is a ~45 kDa protein. Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. For research use only.

Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.

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