Description
Human DOCK2 Recombinant Protein (N-His)
Human DOCK2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile390-Glu635, with an N-terminal His tag. Predicted molecular weight: 26.34 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Dedicator of cytokinesis protein 2 (DOCK2) is a ~211 kDa protein. Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. For research use only.
Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
| Product Name: | Human DOCK2 Recombinant Protein (N-His) |
| SKU: | GXRP02647 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Dedicator of cytokinesis protein 2, DOCK2, KIAA0209 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ile390-Glu635 |
| Calculated MW: | 26.34 kDa |
| UniProt: | Q92608 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
